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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
25.15
Human Site:
T303
Identified Species:
36.89
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
T303
S
G
L
P
R
M
K
T
V
L
L
V
G
G
L
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
T303
S
G
L
P
R
M
K
T
V
L
L
V
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
V52
C
G
I
K
I
V
V
V
D
E
A
D
T
M
L
Dog
Lupus familis
XP_537128
620
68704
T304
S
G
L
P
R
M
K
T
V
L
L
V
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
T303
S
G
L
P
R
M
K
T
V
L
L
V
G
G
L
Rat
Rattus norvegicus
Q66HG7
589
65047
T303
R
G
L
P
R
M
K
T
V
L
L
V
G
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
N272
I
I
R
A
L
E
E
N
K
T
P
S
A
L
I
Chicken
Gallus gallus
XP_422189
625
69278
T309
A
G
L
P
N
M
R
T
V
L
L
V
G
G
L
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
V444
S
K
S
L
A
L
R
V
V
C
V
Y
G
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
I349
A
F
E
S
Y
L
K
I
G
I
V
Y
G
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
T328
K
R
M
L
S
M
K
T
A
L
L
V
G
G
L
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
G258
E
L
I
V
G
T
P
G
R
L
I
D
L
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
L239
R
I
Q
Q
G
V
E
L
I
I
G
T
P
G
R
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
A293
R
G
C
D
L
L
V
A
T
P
G
R
L
N
D
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
V400
A
T
P
L
G
F
T
V
V
S
I
V
G
G
H
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
13.3
100
N.A.
100
93.3
N.A.
0
80
0
26.6
N.A.
20
N.A.
N.A.
60
P-Site Similarity:
100
100
26.6
100
N.A.
100
93.3
N.A.
13.3
93.3
0
46.6
N.A.
46.6
N.A.
N.A.
66.6
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
26.6
P-Site Similarity:
20
N.A.
N.A.
33.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
7
7
0
0
7
7
0
7
0
7
0
7
% A
% Cys:
7
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
7
0
0
13
0
0
7
% D
% Glu:
7
0
7
0
0
7
13
0
0
7
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
19
0
0
7
7
0
13
0
63
69
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
13
13
0
7
0
0
7
7
13
13
0
0
0
7
% I
% Lys:
7
7
0
7
0
0
44
0
7
0
0
0
0
0
0
% K
% Leu:
0
7
38
19
13
19
0
7
0
50
44
0
13
13
50
% L
% Met:
0
0
7
0
0
44
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
7
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
7
38
0
0
7
0
0
7
7
0
7
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
7
7
0
32
0
13
0
7
0
0
7
0
0
7
% R
% Ser:
32
0
7
7
7
0
0
0
0
7
0
7
0
0
0
% S
% Thr:
0
7
0
0
0
7
7
44
7
7
0
7
7
0
13
% T
% Val:
0
0
0
7
0
13
13
19
50
0
13
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _